The Foundation for Innovation in Cardiometabolism and Nutrition (IHU ICAN) is one of Europe’s leading institutes in cardiovascular, metabolic, and nutritional diseases, bringing together teams of fundamental and clinical researchers. 

Created in 2011, ICAN is located at the heart of the Pitié Salpêtrière Hospital and draws on the expertise of its founding members: Assistance Publique Hôpitaux de Paris (AP-HP), The National Institute of Health and Medical Research (INSERM) and Sorbonne University (SU) to carry out its mission. The ICAN has structured cutting-edge platforms for translational research, particularly for imaging cardiometabolic tissues and integrating clinical and multi-omics data.

Our mission is to accelerate the translation of preclinical and clinical discoveries directly to the care of patients suffering from cardiovascular and metabolic diseases. In 2019, ICAN supported the establishment of the AP-HP NASH clinic, which resembles an interdisciplinary medical team offering optimized diagnosis and management of the fatty liver disease.


Thus, ICAN shares the vision of the GRIPonMASH project to transform the detection and diagnosis of NAFLD patients and innovate personalised medicine approaches. Towards this aim, ICAN will contribute to the GRIPonMASH cohort by enrolling 1000 high-risk patients and providing paramount medical expertise.